Pular para o conteúdo
Merck

DAZL

deleted in azoospermia-like

Sinônimos:
DAZH, DAZL1, DAZLA, SPGYLA
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1618) Summary: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
  • Mouse(13164) deleted in azoospermia-like
  • Rat(680486) deleted in azoospermia-like
  • Zebrafish(58039) deleted in azoospermia-like
  • chicken(374054) deleted in azoospermia-like
  • cow(530116) deleted in azoospermia-like
  • dog(477055) deleted in azoospermia-like
  • sheep(100885769) deleted in azoospermia-like
  • domestic guinea pig(100722319) deleted in azoospermia-like
  • naked mole-rat(101723796) deleted in azoospermia-like

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-DAZL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-DAZL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-DAZL antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Dazl,
Espécies
mouse
MISSION® esiRNA, targeting human DAZL,
Espécies
human