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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

Sinônimos:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Espécies:
Human CHUK (1147), Mouse Chuk (12675), Rat Chuk (309361), Zebrafish chuk (393287), cow CHUK (281073), Horse CHUK (100070393), dog CHUK (477796), chicken CHUK (423669), domestic cat CHUK (101095617), sheep CHUK (101111143) ...Mais
ID UniProtKB:
O15111, O14666, Q13132, Q5W0I4, Q92467
ID do gene:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
SAB5700523
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
Reatividade de espécies
human
Aplicação
western blot
SAB5702171
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
Reatividade de espécies
mouse
Aplicação
western blot
SAB4300396
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
SAB4301429
Anti-phospho-IKK-α/β (pSer180/181) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
ZRB1673
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicação
affinity binding assay
immunohistochemistry
inhibition assay
western blot

Proteins

Número do produto
Descrição
Espécies
14-461-M
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Espécies
human
SRP5040
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EMU041031
MISSION® esiRNA, targeting mouse Chuk,
Espécies
mouse
EHU229471
MISSION® esiRNA, targeting human CHUK,
Espécies
human

Small Molecule - Substrate

Número do produto
Descrição
Espécies
12-459
IKK Substrate Peptide, ,
Espécies
human