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Merck

CCND3

cyclin D3

Sinônimos:
Espécies:
ID UniProtKB:
ID do gene:
  • Human(896) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  • Mouse(12445) cyclin D3
  • Rat(25193) cyclin D3
  • Zebrafish(449996) cyclin D3
  • cow(540547) cyclin D3
  • domestic cat(101101311) cyclin D3
  • dog(608847) cyclin D3
  • chicken(419928) cyclin D3
  • naked mole-rat(101708062) cyclin D3
  • domestic guinea pig(100718785) cyclin D3
  • sheep(100147798) cyclin D3
  • Domestic Rabbit(100009038) cyclin D3

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Cyclin D3 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
Anti-CCND3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-Cyclin D3 antibody, Rabbit monoclonal, clone SP207, recombinant, expressed in proprietary host, affinity isolated antibody,
Reatividade de espécies
bovine, human, mouse, rat
Aplicação
flow cytometry
immunohistochemistry

western blot
Anti-CCND3 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-Cyclin D3 (pThr283) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot

Proteins

Número do produto
Descrição
Espécies
CDK4/CyclinD3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CCND3,
Espécies
human