ASPH
aspartate beta-hydroxylase
Sinônimos:
AAH, BAH, CASQ2BP1, HAAH, JCTN, junctin
Espécies:
Human ASPH (444), Mouse Asph (65973), Rat Asph (312981), Zebrafish asph (323659), fruit fly Asph (36778), cow ASPH (286771), Horse ASPH (100065909), domestic cat ASPH (101100695), dog ASPH (403846), chicken ASPH (421142) ...Mais
ID UniProtKB:
ID do gene:
- Human(444) Summary: This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. [provided by RefSeq, Sep 2009]
- Mouse(65973) aspartate-beta-hydroxylase
- Rat(312981) aspartate-beta-hydroxylase
- Zebrafish(323659) aspartate beta-hydroxylase
- fruit fly(36778) Aspartyl beta-hydroxylase
- cow(286771) aspartate beta-hydroxylase
- Horse(100065909) aspartate beta-hydroxylase
- domestic cat(101100695) aspartate beta-hydroxylase
- dog(403846) aspartate beta-hydroxylase
- chicken(421142) aspartate beta-hydroxylase
- domestic guinea pig(100726813) aspartate beta-hydroxylase
- naked mole-rat(101725986) aspartate beta-hydroxylase
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Antibodies
Product Number
Descrição
Reatividade de espécies
Aplicação
Anti-ASPH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-ASPH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-ASPH, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
western blot
Anti-ASPH, affinity isolated antibody,
Reatividade de espécies
dog, human, rat
Aplicação
western blot
esiRNA
Product Number
Descrição
Espécies