AR
androgen receptor
Sinônimos:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Espécies:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), Zebrafish ar (100005148), chicken AR (422165), fruit fly ar (44503), domestic cat AR (101081787), cow AR (280675), Horse AR (100033980), domestic cat AR (751827) ...Mais
ID UniProtKB:
ID do gene:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- fruit fly(44503) abdomen rotatum
- domestic cat(101081787) androgen receptor
- cow(280675) androgen receptor
- Horse(100033980) androgen receptor
- domestic cat(751827) androgen receptor
- dog(403588) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- sheep(443042) androgen receptor
- domestic guinea pig(100726891) androgen receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Número do produto
Descrição
Espécies
Small Molecule - Agonist
Número do produto
Descrição
Espécies
Cyproterone acetate for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Small Molecule - Antagonist
Número do produto
Descrição
Espécies
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody,
Reatividade de espécies
dog, human, mouse, pig, rabbit, rat
Aplicação
immunohistochemistry
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal, culture supernatant, Upstate®,
Reatividade de espécies
human
Aplicação
western blot
Anti-Androgen Receptor antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-Androgen Receptor antibody, Rabbit monoclonal, clone SP107, recombinant, expressed in proprietary host, affinity isolated antibody,
Reatividade de espécies
dog, human, mouse, pig, rat
Aplicação
immunohistochemistry
Anti-Androgen Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ChIP
ELISA
immunohistochemistry
western blot
ELISA
immunohistochemistry
western blot
Small Molecule - Blocker
Número do produto
Descrição
Espécies
Small Molecule - Inhibitor
Small Molecule - Ligand
Número do produto
Descrição
Espécies