- Establishment of a three-step method to evaluate effects of chemicals on development of zebrafish embryo/larvae.
Establishment of a three-step method to evaluate effects of chemicals on development of zebrafish embryo/larvae.
Chemosphere (2017-08-07)
Guangyu Li, Huike Ye, Guanyong Su, Zhihua Han, Congxin Xie, Bingsheng Zhou, Robert J Letcher, John P Giesy, Hongxia Yu, Chunsheng Liu
PMID28780448
ABSTRACT
Core endpoints in zebrafish embryos are crucial indicators in screening harmful effects of chemicals. In this study, we established a three-step process to more quantitatively and less-subjective determine effects of chemicals on phenotypes of developing zebrafish embryos. Embryos were exposed to each of two concentrations of the representative chemicals cadmium chloride (CdCl
MATERIALS