Estimation of human exposure to styrene and ethylbenzene.

Estimation of human exposure to styrene and ethylbenzene.

Toxicology (2000-04-27)

W Tang, I Hemm, G Eisenbrand

ABSTRACT

In the present studies, human exposure to styrene and to ethylbenzene (EB) is assessed on the basis of literature data. Total styrene and total EB exposure result from inhalation and from food intake. Styrene and EB inhaled represent the greatest proportion of the total intake. Styrene and EB content in food is mainly caused by migration from polymer packaging material. The daily styrene exposure is estimated to range from 18.2 to 55.2 microg/person, corresponding to an annual exposure of 6.7 to 20.2 mg/person. The daily EB exposure is estimated to be about 130 microg/person, corresponding to an annual exposure of 46 mg/person. Cigarette smoking is another important factor for styrene and EB intake by smokers.

MATERIALS

Product Number

Brand

Product Description

296848

Sigma-Aldrich

Ethylbenzene, anhydrous, 99.8%

03079

Supelco

Ethylbenzene, analytical standard

PHR1229

Supelco

Ethylbenzene, Pharmaceutical Secondary Standard; Certified Reference Material

E12508

Sigma-Aldrich

Ethylbenzene, ReagentPlus^®, 99%

717959

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 1% in chloroform-d (99.8 atom % D)

736198

Supelco

Ethylbenzene solution, NMR reference standard, 10% in chloroform-d (99.8 atom % D), NMR tube size 5 mm × 8 in. , ultra-thin wall

733768

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 10% in chloroform-d (99.8 atom % D), NMR tube size 10 mm × 8 in.

717967

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.1 %

708046

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 10% in chloroform-d (99.8 atom % D)

708054

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d ("100%", 99.96 atom % D)

487120

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 8 mm × 8 in.

551341

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 5% in chloroform-d (99.8 atom % D), TMS 2 %, NMR tube size 5 mm × 8 in.

612065

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 10 mm × 8 in.

612480

Supelco

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), chromium(III) acetylacetonate 0.1 mg/mL, TMS 0.01 %, NMR tube size 5 mm × 8 in.

714917

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 5 mm × 8 in. , ultra-thin wall

710725

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 5% in chloroform-d (99.8 atom % D), TMS 1 %, NMR tube size 5 mm × 7 in.

487104

Supelco

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 5 mm × 8 in.