AB1094
Anti-Myosin X Antibody
serum, from rabbit
Synonym(s):
Unconventionnal myosin-X, Unconventional myosin-10
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, rat, human
technique(s)
western blot: suitable
GenBank accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... MYO10(4651)
General description
Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006).
Specificity
Cat. No. AB1094 recognizes human Myosin X.
Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested.
Immunogen
Epitope: a.a. 936-953
KLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X.
Application
Detect Myosin X using this Anti-Myosin X Antibody validated for use in WB.
Quality
Evaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X.
Target description
~ 108 kDa
Storage and Stability
Maintain at -20°C for up to 1 year from date of receipt.
Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Analysis Note
Control
Human head/neck lysate.
Human head/neck lysate.
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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