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Merck

SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

Synonyms:
NAT1, NET, NET1, SLC6A5
Species:
UniProtKB ID:
Gene ID:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

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Small Molecule - Antagonist

Product Number
Description
Species
4,4′-Diaminodiphenylmethane, ≥97.0% (GC),
Species
mouse, rat
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
6-Methoxyharmalan, crystalline,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SLC6A2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-Norepinephrine Antibody, serum, Chemicon®,
Species Reactivity
human, rat
Application
immunohistochemistry
Anti-Norepinephrine Transporter Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Debrisoquine sulfate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Debrisoquine sulfate, ,
Species
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SLC6A2,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
Guanethidine monosulfate, British Pharmacopoeia (BP) Reference Standard,
Species
human