RAD51
RAD51 recombinase
Synonyms:
BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA
Species:
Human RAD51 (5888), Mouse Rad51 (19361), Rat Rad51 (499870), cow RAD51 (514749), sheep RAD51 (101109275), Domestic Rabbit RAD51 (100008661), naked mole-rat Rad51 (101715048), domestic guinea pig Rad51 (100716391), Thale Cress RAD51 (832208), chicken RAD51 (396086) ...More
UniProtKB ID:
Gene ID:
- Human(5888) Summary: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
- Mouse(19361) RAD51 homolog
- Rat(499870) RAD51 recombinase
- cow(514749) RAD51 homolog (S. cerevisiae)
- sheep(101109275) RAD51 homolog (S. cerevisiae)
- Domestic Rabbit(100008661) RAD51 homolog (S. cerevisiae)
- naked mole-rat(101715048) RAD51 homolog (S. cerevisiae)
- domestic guinea pig(100716391) RAD51 homolog (S. cerevisiae)
- Thale Cress(832208) DNA repair protein RAD51-like 1
- chicken(396086) RAD51 homolog (S. cerevisiae)
- dog(403568) RAD51 homolog (S. cerevisiae)
- domestic cat(101089015) RAD51 homolog (S. cerevisiae)
- Zebrafish(406487) RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RAD51 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-RAD51 Antibody, clone 1M8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-RAD51 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-RAD51 (pTyr315) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-RAD51 antibody produced in mouse, clone 4C11-B4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species