IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
Synonyms:
IMPD2, IMPDH-II
Species:
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), Zebrafish impdh2 (317745), Horse IMPDH2 (100063255), cow IMPDH2 (511969), domestic cat IMPDH2 (101080693), chicken IMPDH2 (416058), dog IMPDH2 (476630), domestic guinea pig Impdh2 (100730768) ...More
UniProtKB ID:
Gene ID:
- Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
- Mouse(23918) inosine 5'-phosphate dehydrogenase 2
- Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
- Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
- cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
- domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
- chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
- dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
- domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
- naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
- sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-IMPDH2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-IMPDH2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
Species Reactivity
human
Application
Small Molecule - Inhibitor
Product Number
Description
Species
6-Thioguanine, Hybri-Max™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Species
human
Proteins
Product Number
Description
Species
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
Species
human