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Merck

HDAC6

histone deacetylase 6

Synonyms:
HD6
Species:
UniProtKB ID:
Gene ID:
  • Human(10013) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
  • Mouse(15185) histone deacetylase 6
  • Rat(84581) histone deacetylase 6
  • Zebrafish(565482) histone deacetylase 6
  • domestic cat(101084086) histone deacetylase 6
  • cow(513602) histone deacetylase 6
  • dog(480907) histone deacetylase 6
  • fruit fly(32461) CG6170 gene product from transcript CG6170-RA
  • domestic guinea pig(100717988) histone deacetylase 6
  • naked mole-rat(101708442) histone deacetylase 6
  • sheep(101109245) histone deacetylase 6

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 1E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-HDAC6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 3A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-HDAC6 Antibody, clone 9V1W2, Rabbit Monoclonal, ,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-HDAC6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
SAHA, ≥98% (HPLC),
Species
human
Trichostatin A, ≥98% (HPLC), from Streptomyces sp.,
Species
human, mouse, rat
CI−994, ≥98% (HPLC), powder,
Species
human
Romidepsin, ≥98% (HPLC),
Species
human

Proteins

Product Number
Description
Species
HDAC6 H216A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE),
Species
human
HDAC6 H611A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥79% (SDS-PAGE),
Species
human
HDAC-6 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HDAC6,
Species
human
MISSION® esiRNA, targeting mouse Hdac6,
Species
mouse