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Merck

GPC3

glypican 3

Synonyms:
DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Species:
Human GPC3 (2719), Mouse Gpc3 (14734), Rat Gpc3 (25236), domestic guinea pig Gpc3 (100726246), sheep GPC3 (101119285), Domestic Rabbit GPC3 (100351858), Zebrafish gpc3 (387365), cow GPC3 (615239), domestic cat GPC3 (101094739), dog GPC3 (481056)
UniProtKB ID:
P51654, C9JLE3, G3V1R0, Q2L880, Q2L882
Gene ID:
  • Human(2719) Summary: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
  • Mouse(14734) glypican 3
  • Rat(25236) glypican 3
  • domestic guinea pig(100726246) glypican 3
  • sheep(101119285) glypican 3
  • Domestic Rabbit(100351858) glypican 3
  • Zebrafish(387365) glypican 3
  • cow(615239) glypican 3
  • domestic cat(101094739) glypican 3
  • dog(481056) glypican 3
  • chicken(770863) glypican 3

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ELISA

Product Number
Description
Species
RAB1055
Human Glypican 3 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1402788
Monoclonal Anti-GPC3 antibody produced in mouse, clone 2C12, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
MABC667
Anti-GPC3 Antibody, clone 9C2, ascites fluid, clone 9C2, from mouse,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence
immunohistochemistry
western blot
SAB5500115
Anti-Glypican-3 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP86, affinity isolated antibody,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot
SAB2108511
Anti-GPC3, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
HPA006316
Anti-GPC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
G1921
Glypican 3 human, recombinant, expressed in NSO cells,
Species
human
SRP0610
Monkey (M. fascicularis) GPC3, His-Tag, recombinant, expressed in HEK 293 cells,
Species
mouse

esiRNA

Product Number
Description
Species
EMU022581
MISSION® esiRNA, targeting mouse Gpc3,
Species
mouse
EHU001531
MISSION® esiRNA, targeting human GPC3,
Species
human