Skip to Content
Merck

ADRB2

adrenoceptor beta 2, surface

Synonyms:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Species:
UniProtKB ID:
Gene ID:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
Terbutaline sulfate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Salbutamol, European Pharmacopoeia (EP) Reference Standard,
Species
human
Levalbuterol hydrochloride, ≥98% (HPLC),
Species
human
Salmeterol xinafoate, ≥98% (HPLC), solid,
Species
human
Salmeterol xinafoate, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Species
human
Propranolol hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
(±)-Propranolol hydrochloride, analytical standard,
Species
human
Esmolol hydrochloride, ≥98% (HPLC), solid,
Species
human
Nadolol, analytical standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor β2 (pSer346) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Description
Species
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Species
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Species
human
Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Propafenone hydrochloride, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Adrb2,
Species
mouse
MISSION® esiRNA, targeting human ADRB2,
Species
human