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BP1100

Hydroxychloroquine sulfate

British Pharmacopoeia (BP) Reference Standard

Synonyme(s) :

7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate

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About This Item

Formule empirique (notation de Hill):
C18H26ClN3O · H2SO4
Numéro CAS:
Poids moléculaire :
433.95
Numéro MDL:
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Agence

BP

Famille d'API

hydroxychloroquine

Forme

solid

Durée de conservation

limited shelf life, expiry date on the label

Conditionnement

pkg of 100 mg

Fabricant/nom de marque

BP

Couleur

off-white

Pf

238-241 °C

Solubilité

water: soluble

Application(s)

pharmaceutical
pharmaceutical small molecule

Format

neat

Conditions d'expédition

ambient

Température de stockage

2-8°C

Chaîne SMILES 

OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

Clé InChI

JCBIVZZPXRZKTI-UHFFFAOYSA-N

Informations sur le gène

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Description générale

Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydroxychloroquine sulfate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Hydroxychloroquine Tablets
  • Actions biochimiques/physiologiques

    Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

    Conditionnement

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Autres remarques

    Sales restrictions may apply.

    Pictogrammes

    Exclamation mark

    Mention d'avertissement

    Warning

    Mentions de danger

    Classification des risques

    Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

    Code de la classe de stockage

    11 - Combustible Solids

    Classe de danger pour l'eau (WGK)

    WGK 3

    Point d'éclair (°F)

    Not applicable

    Point d'éclair (°C)

    Not applicable


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    Certificats d'analyse (COA)

    Lot/Batch Number

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    Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

    Consulter la Bibliothèque de documents

    Famotidine
    British Pharmacopeia
    British Pharmacopoeia, 44(12), 1000-1004 (2020)
    A rapid and reliable method for the quantitation of hydroxychloroquine in serum using turbulent flow liquid chromatography-tandem mass spectrometry
    Fuzery AK, et al.
    Clinica Chimica Acta; International Journal of Clinical Chemistry, 421 (2013)
    Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
    Charlier B,et al.
    Biomedical Chromatography, 32(8), e4258-e4258 (2018)
    Compatibility study of hydroxychloroquine sulfate with pharmaceutical excipients using thermal and nonthermal techniques for the development of hard capsules
    Moraes ANF, et al.
    Journal of Thermal Analysis and Calorimetry, 421 (2019)

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