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A6661

Sigma-Aldrich

Albumin, dinitrophenyl

lyophilized powder

Synonyme(s) :

DNP-albumin human

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.25

Source biologique

human

Forme

lyophilized powder

Ampleur du marquage

30-40 mol DNP per mol albumin

Numéro d'accès UniProt

Température de stockage

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

Clé InChI

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Informations sur le gène

human ... ALB(213)

Application

Albumin, dinitrophenyl has been used to assess degranulation from rat mast cells by treatment of:
  • bakkenolide B
  • 4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1)
  • mifepristone
Used for detection in immunological analyses. Can be used as an immunological challenge to activate basophils via the IgE receptor.

Remarque sur l'analyse

Source material has tested negative for HIV and HBsAg

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Kyoung-Pil Lee et al.
Journal of ethnopharmacology, 148(3), 890-894 (2013-05-29)
To elucidate the anti-allergic and anti-inflammatory effects of Petasites genus, we studied the effects of several compounds isolated from Petasites japonicas leaves. Bakkenolide B was isolated from Petasites japonicus leaves. Antigen-induced degranulation was measured in RBL-2H3 mast cells by measuring
B Jabril-Cuenod et al.
The Journal of biological chemistry, 271(27), 16268-16272 (1996-07-05)
Antigen receptors on T- and B-cells activate Ras through a signaling pathway that results in the tyrosine phosphorylation of Shc and the formation of a complex of Shc with the Grb2 adaptor protein. The high affinity receptor for immunoglobulin E
Little, S.R. and Eisen, H.N.
Methods Immunol. Immunochem., 1, 128-128 (1967)
Xuan Che et al.
International journal of medical sciences, 17(2), 224-233 (2020-02-11)
Background: Adenomyosis is a quite common gynecological disorder and above 30% of patients have typical secondary and progressive dysmenorrhea. Current treatments still have many disadvantages and thereby the novel treatment aiming to relieve dysmenorrhea still needs to be further investigated.
G J Heywood et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 51(4), 176-181 (2002-06-13)
Nicorandil is a potassium channel opener and nitric oxide (NO) donor, and the hypothesis was tested that these modes of action may inhibit cellular degranulation and release of tumour necrosis factor-alpha (TNF-alpha). TNF-alpha and beta-hexosaminidase secretion were measured from rat

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