BP878

Tioguanine

British Pharmacopoeia (BP) Reference Standard

• Synonyme(s) : 6-Thioguanine, 2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol
• Formule empirique (notation de Hill): C₅H₅N₅S
• Numéro CAS: 154-42-7
• Poids moléculaire : 167.19
• Numéro Beilstein : 157765
• Numéro MDL: MFCD00233553
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: thioguanine, tioguanine
• Forme: powder
• Durée de conservation: limited shelf life, expiry date on the label
• Fabricant/nom de marque: BP
• Pf: ≥300 °C (lit.)
• Application(s): pharmaceutical
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: NC1=Nc2nc[nH]c2C(=S)N1
• InChI: 1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
• Clé InChI: WYWHKKSPHMUBEB-UHFFFAOYSA-N
• Informations sur le gène: human ... IMPDH1(3614) , IMPDH2(3615)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tioguanine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Tioguanine

Tioguanine Tablets

Actions biochimiques/physiologiques

Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.

Conditionnement

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 + P330 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable