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222461

Sigma-Aldrich

Murexide

ACS reagent

Synonyme(s) :

5,5′-Nitrilodibarbituric acid monoammonium salt, Ammonium purpurate

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About This Item

Formule empirique (notation de Hill):
C8H8N6O6
Numéro CAS:
3051-09-0
Poids moléculaire :
284.19
Numéro C.I. (Colour Index):
56085
Numéro Beilstein :
3831445
Numéro CE :
221-266-6
Numéro MDL:
MFCD00012777
Code UNSPSC :
12171500
ID de substance PubChem :
24853333
Nomenclature NACRES :
NA.47

Qualité

ACS reagent

Niveau de qualité

200

Forme

powder

Technique(s)

titration: suitable

Pf

>300 °C (lit.)

λmax

525 nm

Adéquation

passes test for complexometric indicator

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

N.OC1=C(\N=C2\C(=O)NC(=O)NC2=O)C(=O)NC(=O)N1

InChI

1S/C8H5N5O6.H3N/c14-3-1(4(15)11-7(18)10-3)9-2-5(16)12-8(19)13-6(2)17;/h(H2,10,11,14,15,18)(H3,12,13,16,17,19);1H3

Clé InChI

LJYRLGOJYKPILZ-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Murexide is the ammonium salt of purpuric acid that appears as a slightly reddish-purple powder and is soluble in water. It is mainly used as an indicator for complexometric titrations to measure water hardness and as a colorant/pigment in the dye industry.

Application

Murexide is used for the histochemical staining of calcium in the skeleton. It is suitable for staining the hemijaws for dental caries scoring.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCF9241
BCCF0688
BCCD0161
BCBV6336
BCBS5394V

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F D Coffman et al.
Biochemistry, 27(16), 6179-6187 (1988-08-09)
An insulin hexamer containing one B10-bound Co(III) ion and one unoccupied B10 site has been synthesized. The properties of the monosubstituted hexamer show that occupancy of only one B10 site by Co3+ is sufficient to stabilize the hexameric form under
A Hirota et al.
The Journal of general physiology, 94(4), 597-631 (1989-10-01)
Two new Ca indicators, purpurate-3,3'diacetic acid (PDAA) and 1,1'-dimethylpurpurate-3,3'diacetic acid (DMPDAA), were synthesized and used to measure Ca transients in frog cut muscle fibers. These indicators are analogues of the purpurate components of murexide and tetramethylmurexide, in which two acetate
H Gusman et al.
Biochimica et biophysica acta, 1545(1-2), 86-95 (2001-05-09)
Histatins are small histidine-rich salivary polypeptides which exhibit antimicrobial activity against Candida albicans. This antimicrobial activity has been ascribed in part to a high content of basic amino acids. However, unlike most other antimicrobial proteins histatins have a high content
Cédric R H Lamboley et al.
Cell calcium, 50(6), 530-547 (2011-11-01)
One aim of this article was to determine the resting concentration of free Ca(2+) in the sarcoplasmic reticulum (SR) of frog cut skeletal muscle fibers ([Ca(2+)](SR,R)) using the calcium absorbance indicator dye tetramethylmurexide (TMX). Another was to determine the ratio
J Maylie et al.
The Journal of general physiology, 89(1), 145-176 (1987-01-01)
The Ca indicator tetramethylmurexide was introduced into cut fibers, mounted in a double-Vaseline-gap chamber, by diffusion from the end-pool solutions. The indicator diffused rapidly to the central region of a fiber where optical recording was done and, if removed, diffused
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