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03880590

Luteolin

primary reference standard

Synonyme(s) :

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Formule empirique (notation de Hill):
C15H10O6
Numéro CAS:
491-70-3
Poids moléculaire :
286.24
Numéro Beilstein :
292084
Numéro CE :
207-741-0
Numéro MDL:
MFCD00017309
Code UNSPSC :
85151701
ID de substance PubChem :
329747828
Nomenclature NACRES :
NA.24

Qualité

primary reference standard

Durée de conservation

limited shelf life, expiry date on the label

Fabricant/nom de marque

HWI

Pf

~330 °C (lit.)

Application(s)

food and beverages

Chaîne SMILES 

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

Clé InChI

IQPNAANSBPBGFQ-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Autres remarques

This compound is commonly found in plants of the genus: achillea

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
HWI03169
HWI02485-1
HWI02485
HWI02293
HWI02063-1

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Kaempferol United States Pharmacopeia (USP) Reference Standard

USP

1354900

Kaempferol

Diosmetin

Sigma-Aldrich

D7321

Diosmetin

Kaempferol analytical standard

Supelco

96353

Kaempferol

Acide citrique anhydrous for synthesis

Sigma-Aldrich

8.18707

Acide citrique

Lien Verschooten et al.
PloS one, 7(10), e48264-e48264 (2012-10-31)
Flavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities. In this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell death in a model of human cutaneous squamous cell carcinoma
Poyil Pratheeshkumar et al.
PloS one, 7(12), e52279-e52279 (2013-01-10)
Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid found in fruits and vegetables. We studied the antiangiogenic activity of luteolin using in vitro
Theoharis C Theoharides et al.
Advances in experimental medicine and biology, 601, 423-430 (2007-08-24)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but recent evidence indicates that Th2 T cells, mostly associated with allergic reactions, are also involved. Mast cells are involved in allergic and
Yong Lin et al.
Current cancer drug targets, 8(7), 634-646 (2008-11-11)
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
Benguo Liu et al.
Food chemistry, 141(2), 900-906 (2013-06-26)
The formation of supramolecular inclusion complexes between luteolin and five cyclodextrins namely β-cyclodextrin (β-CD), methyl-β-cyclodextrin (M-β-CD), hydroxyethyl-β-cyclodextrin (HE-β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD) and glucosyl-β-cyclodextrin (G-β-CD) was investigated. Results from phase-solubility studies showed that luteolin formed 1:1 stoichiometric inclusion complexes with these cyclodextrins
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