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Documents

03762

2,6-Di-tert-butyl-4-methylphenol

Name: 2,6-Di-<I>tert</I>-butyl-4-methylphenol
Brand: SIAL

tested according to Ph. Eur.

Synonyme(s) :

Butylhydroxytoluène, Hydroxytoluène butylé

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About This Item

Formule linéaire :

[(CH₃)₃C]₂C₆H₂(CH₃)OH

Numéro CAS:

128-37-0

Poids moléculaire :

220.35

Numéro Beilstein :

1911640

Numéro CE :

204-881-4

Numéro MDL:

MFCD00011644

Code UNSPSC :

12352300

ID de substance PubChem :

329747800

Nomenclature NACRES :

NA.21

Agence

USP/NF
tested according to Ph. Eur.

Niveau de qualité

200

Densité de vapeur

7.6 (vs air)

Pression de vapeur

<0.01 mmHg ( 20 °C)

Température d'inflammation spontanée

878 °F

Point d'ébullition

265 °C (lit.)

Pf

69-73 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

Clé InChI

NLZUEZXRPGMBCV-UHFFFAOYSA-N

Informations sur le gène

human ... CAPN1(823)
rat ... Capn1(29153) , Nos1(24598)

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Application

Quantitative analysis of residual butylated hydroxytoluene and butylated hydroxyanisole in Salmo salar, milk, and butter by liquid chromatography-tandem mass spectrometry.: This study provides a quantitative analysis of residual 2,6-Di-tert-butyl-4-methylphenol (BHT) and butylated hydroxyanisole (BHA) in various food products. The research highlights the presence and concentration of these antioxidants in fish, milk, and butter, demonstrating their widespread use in food preservation (Galal et al., 2024).

The key factors of solid nanodispersion for promoting the bioactivity of abamectin.: This research investigates the use of BHT in solid nanodispersions to enhance the bioactivity of abamectin, a widely used insecticide. The study identifies key factors that improve the stability and effectiveness of the formulation, suggesting applications in agricultural biotechnology (Ding et al., 2024).

Pictogrammes

GHS09

Mention d'avertissement

Warning

Mentions de danger

H410

Conseils de prudence

P273 - P391 - P501

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

260.6 °F - open cup

Point d'éclair (°C)

127 °C - open cup

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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The antioxidant butylated hydroxytoluene protects against atherosclerosis.

I Björkhem et al.

Arteriosclerosis and thrombosis : a journal of vascular biology, 11(1), 15-22 (1991-01-01)

Rabbits fed a 1% cholesterol diet with or without the antioxidant butylated hydroxytoluene (BHT) developed typical atherosclerotic lesions. The addition of BHT gave higher levels of total cholesterol (+40%), triglycerides (+250%), low density lipoprotein (LDL), and very low density lipoprotein

Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model.

Li Li et al.

Circulation, 105(7), 861-867 (2002-02-21)

Current epidemiological data suggest that dental infections affecting tooth-supporting tissues (periodontitis) can disseminate into the systemic circulation and thereby contribute to atherosclerosis progression. To test this hypothesis, we investigated the effect of repeated systemic inoculations with Porphyromonas gingivalis (Pg), a

Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents.

A M Vijesh et al.

European journal of medicinal chemistry, 46(11), 5591-5597 (2011-10-05)

In the present study two new series of Hantzsch 1,4-dihydropyridine derivatives (1,4-DHPs) containing substituted pyrazole moiety (4a-f and 5a-f) were synthesized by the reaction of 3-aryl-1H-pyrazole-4-carbaldehydes with 1,3-dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized

Highly brominated mono- and bis-phenols from the marine red alga Symphyocladia latiuscula with radical-scavenging activity.

Xiao-Juan Duan et al.

Journal of natural products, 70(7), 1210-1213 (2007-07-03)

Four new highly brominated and fully substituted mono- and bis-phenols, 1-(2,3,6-tribromo-4,5-dihydroxybenzyl)pyrrolidin-2-one (1), 1,2-bis(2,3,6-tribromo-4,5-dihydroxyphenyl)ethane (2), 6-(2,3,6-tribromo-4,5-dihydroxybenzyl)-2,5-dibromo-3,4-dihydroxybenzyl methyl ether (3), and 2,3,6-tribromo-4,5-dihydroxybenzyl methyl sulfone (4), were characterized from the marine red alga Symphyocladia latiuscula. In addition, five known bromophenols, bis(2,3,6-tribromo-4,5-dihydroxyphenyl)methane (5), bis(2,3,6-tribromo-4,5-dihydroxybenzyl)

Effects of feeding Spodoptera littoralis on lima bean leaves: IV. Diurnal and nocturnal damage differentially initiate plant volatile emission.

Gen-ichiro Arimura et al.

Plant physiology, 146(3), 965-973 (2008-01-01)

Continuous mechanical damage initiates the rhythmic emission of volatiles in lima bean (Phaseolus lunatus) leaves; the emission resembles that induced by herbivore damage. The effect of diurnal versus nocturnal damage on the initiation of plant defense responses was investigated using

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