8.17019

Poly(éthylène glycol)

3000, EMPROVE^® ESSENTIAL, Ph. Eur., NF

• Synonyme(s) : PEG
• Formule linéaire : H(OCH₂CH₂)_nOH
• Numéro CAS: 25322-68-3
• Numéro MDL: MFCD00081839
• Code UNSPSC : 13111021
• Numéro de classement CE : 500-038-2

Propriétés

• Agence: NF; Ph. Eur.
• Niveau de qualité: 500
• Pression de vapeur: <0.1 hPa ( 20 °C)
• Gamme de produits: EMPROVE^® ESSENTIAL
• Forme: scales
• Température d'inflammation spontanée: 420 °C
• Poids mol.: average M_n 3000
• Technique(s): API processing | nano-milling: suitable
• pH: 4-7 (20 °C, 100 g/L in H₂O)
• Pf: 55-58 °C
• Température de transition: flash point 270 °C
• Densité: 1.21 g/cm³ at 20 °C
• Application(s): liquid formulation; pharmaceutical; semi-solid formulation; solid formulation; solubility enhancement
• Température de stockage: no temp limit
• Chaîne SMILES: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• Clé InChI: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

Description générale

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyethylene glycol (PEG) is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations. Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more. Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 281.5 °F - closed cup
• Point d'éclair (°C): 138.6 °C - closed cup