05-1946

Anti-USP7 Antibody, clone 1G7

clone 1G7, from mouse

• Synonyme(s) : ubiquitin specific peptidase 7 (herpes virus-associated), Ubiquitin-specific-processing protease 7, ubiquitin specific protease 7 (herpes virus-associated), Herpesvirus-associated ubiquitin-specific protease, Herpes virus-associated ubiquitin-specific pr
• Code UNSPSC : 12352203
• eCl@ss : 32160702

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: 1G7, monoclonal
• Espèces réactives: human
• Réactivité de l'espèce (prédite par homologie): mouse (based on 100% sequence homology)
• Technique(s): immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotype: IgG1κ
• Numéro d'accès NCBI: NP_003461.2
• Numéro d'accès UniProt: Q93009
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... USP7(7874)

Description

Description générale

Ubiquitin carboxyl-terminal hydrolase 7 (USP7) is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates.[Saridakis, 2005] Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, Ubiquitin carboxyl-terminal hydrolase 7 activity generally stabilizes its substrate proteins. Ubiquitin carboxyl-terminal hydrolase 7 is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53.[Canning, 2004]

Spécificité

This antibody recognizes USP7.

Immunogène

Histadine-tagged recombinant protein corresponding to human USP7.

Application

This Anti-USP7 Antibody, clone 1G7 is validated for use in WB, IP, IH for the detection of USP7.

Qualité

Evaluated by Western Blot in HeLa lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected USP7 on 10 µg of HeLa cell lysate.

Description de la cible

~ 128kDa Observed

Forme physique

Format: Purified

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable