Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

Autres documents

365572

Sigma-Aldrich

Methyl 6-methoxy-2-indolecarboxylate

99%

Synonyme(s) :

2-Methoxycarbonyl-6-methoxyindole, 6-Methoxyindole-2-carboxylic acid methyl ester

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):
C11H11NO3
Numéro CAS:
98081-83-5
Poids moléculaire :
205.21
Numéro MDL:
MFCD00134301
Code UNSPSC :
12352100
ID de substance PubChem :
24862540
Nomenclature NACRES :
NA.22

Pureté

99%

Pf

117-119 °C (lit.)

Chaîne SMILES 

COC(=O)c1cc2ccc(OC)cc2[nH]1

InChI

1S/C11H11NO3/c1-14-8-4-3-7-5-10(11(13)15-2)12-9(7)6-8/h3-6,12H,1-2H3

Clé InChI

OPUUCOLVBDQWEY-UHFFFAOYSA-N

Application

Methyl 6-methoxy-2-indolecarboxylate is suitable for use in the production of dyes by Escherichia coli expressing naphthalene dioxygenase (NDO) and toluene dioxygenase (TDO). It is also suitable for use in the production of dyes by Escherichia coli expressing multicomponent phenol hydroxylase (mPH) from Pseudomonas sp. strains KL33 and KL28.
Reactant for preparation of:
  • Benzoxazole containing indole analogs as peroxisome proliferator-activated receptor-γ/δ dual agonists
  • Potent antiproliferative agent against human leukemia K562 cells
  • Indole-indolone scaffold via [3+2] annulation of arynes
  • Latonduine derivatives via intramolecular Heck reaction as possible anticancer agents
  • Arylthioindoles as potent inhibitors of tubulin polymerization
  • Heterocycle-fused derivatives of 1-oxo-1,2,3,4-tetrahydropyrazine via Ugi condensation
  • Indole fatty alcohols (IFAs) as promoters of differentiation of neural stem cell derived neurospheres into neurons. Potential application for treatment of neurodegenerative diseases
  • Light-dependent tumor necrosis factor-α antagonists
  • 2-substituted indole melatonin receptor ligands

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

J Y Kim et al.
Letters in applied microbiology, 36(6), 343-348 (2003-05-20)
To isolate and characterize the phorate [O,O-diethyl-S-(ethylthio)methyl phosphoradiothioate] degrading bacteria from agricultural soil, and their assessment for multifarious biological activities of environmental and agronomic significance. Based on their morphological and biochemical characteristics, the selected isolates PS-1, PS-2 and PS-3 were
J Y Kim et al.
Letters in applied microbiology, 41(2), 163-168 (2005-07-22)
To establish multicomponent phenol hydroxylases (mPHs) as novel biocatalysts for producing dyestuffs and hydroxyindoles such as 7-hydroxyindole (7-HI) from indole and its derivatives. We have isolated Pseudomonas sp. KL33, which possesses a phenol degradation pathway similar to that found in

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique