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SGK1

serum/glucocorticoid regulated kinase 1

Synonymes:
SGK
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6446) Summary: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(20393) serum/glucocorticoid regulated kinase 1
  • Rat(29517) serum/glucocorticoid regulated kinase 1
  • Zebrafish(324140) serum/glucocorticoid regulated kinase 1
  • chicken(395133) serum/glucocorticoid regulated kinase 1
  • domestic cat(101098954) serum/glucocorticoid regulated kinase 1
  • dog(403647) serum/glucocorticoid regulated kinase 1
  • domestic guinea pig(100720058) serum/glucocorticoid regulated kinase 1
  • naked mole-rat(101708117) serum/glucocorticoid regulated kinase 1
  • Domestic Rabbit(100008723) serum/glucocorticoid regulated kinase 1
  • cow(515854) serum/glucocorticoid regulated kinase 1
  • sheep(101107709) serum/glucocorticoid regulated kinase 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-phospho-SGK (pSer422) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-SGK1 Antibody, Upstate®, from rabbit,
Espèces réactives
human, rat
Application
immunoprecipitation (IP)
western blot
Anti-SGK antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-SGK1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-phospho-SGK Antibody, serum, Upstate®,
Espèces réactives
human
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
SGK1 (δ1-59, S422D) Protein, active, 6 µg, Active, N-truncated (missing N-terminal 60 amino acids), His-tagged, human SGK1 fusion protein, containing a S422D mutation, for use in Kinase Assays.,
Espèce(s)
human
SGK1 (δ1-60, S422D), active human, recombinant, expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged), buffered aqueous solution,
Espèce(s)
human
SGK1 (60-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Sgk1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human SGK1,
Espèce(s)
human