PLN
phospholamban
Synonymes:
CMD1P, CMH18, PLB
Espèce(s):
Human PLN (5350), Mouse Pln (18821), Rat Pln (64672), chicken PLN (396378), domestic cat PLN (101097897), dog PLN (414755), domestic guinea pig Pln (100721387), naked mole-rat Pln (101699885), Domestic Rabbit PLN (100009299), cow PLN (100125240)
ID UniProtKB:
ID du gène:
- Human(5350) Summary: The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008]
- Mouse(18821) phospholamban
- Rat(64672) phospholamban
- chicken(396378) phospholamban
- domestic cat(101097897) phospholamban
- dog(414755) phospholamban
- domestic guinea pig(100721387) phospholamban
- naked mole-rat(101699885) phospholamban
- Domestic Rabbit(100009299) phospholamban
- cow(100125240) phospholamban
- sheep(101102067) phospholamban
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-phospho-Phospholamban (Ser16) Antibody, Upstate®, from rabbit,
Espèces réactives
bovine, canine, human, mouse, pig, rabbit, rat
Application
western blot
Anti-Phospholamban Antibody, clone 4J16 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PLN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-Phospho-PLN-T17 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-PLB (pSer16+Thr17) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
immunofluorescence
esiRNA
Référence du produit
Description
Espèce(s)