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Merck

PKD2

polycystic kidney disease 2 (autosomal dominant)

Synonymes:
APKD2, PC2, PKD4, Pc-2, TRPP2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5311) Summary: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
  • Mouse(18764) polycystic kidney disease 2
  • Rat(498328) polycystic kidney disease 2 (autosomal dominant)
  • fruit fly(34651) Polycystic kidney disease gene-2
  • Zebrafish(432387) polycystic kidney disease 2
  • domestic cat(101098948) polycystic kidney disease 2 (autosomal dominant)
  • dog(487852) polycystic kidney disease 2 (autosomal dominant)
  • chicken(422585) polycystic kidney disease 2 (autosomal dominant)
  • cow(530393) polycystic kidney disease 2 (autosomal dominant)
  • sheep(101103569) polycystic kidney disease 2 (autosomal dominant)
  • domestic guinea pig(100714947) polycystic kidney disease 2 (autosomal dominant)
  • naked mole-rat(101726639) polycystic kidney disease 2 (autosomal dominant)
  • Domestic Rabbit(100008872) polycystic kidney disease 2 (autosomal dominant)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PKD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-PKD2 antibody produced in mouse, clone 4C8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot
Anti-Polycystin-L Antibody, serum, Chemicon®,
Espèces réactives
mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-PKD2 Antibody, Upstate®, from rabbit,
Espèces réactives
human
Application
western blot
Anti-PKD2 Rabbit pAb, liquid, Calbiochem®,
Espèces réactives
human
Application

Proteins

Référence du produit
Description
Espèce(s)
PKD2 Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6 tagged, recombinant, full length, human PKD2, for use in Kinase Assays.,
Espèce(s)

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Pkd2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human PKD2,
Espèce(s)
human