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Merck

PDHB

pyruvate dehydrogenase (lipoamide) beta

Synonymes:
PDHBD, PDHE1-B, PHE1B
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5162) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(68263) pyruvate dehydrogenase (lipoamide) beta
  • Rat(289950) pyruvate dehydrogenase (lipoamide) beta
  • cow(613610) pyruvate dehydrogenase (lipoamide) beta
  • sheep(101121975) pyruvate dehydrogenase (lipoamide) beta
  • domestic guinea pig(100733476) pyruvate dehydrogenase (lipoamide) beta
  • naked mole-rat(101714134) pyruvate dehydrogenase (lipoamide) beta
  • Zebrafish(406428) pyruvate dehydrogenase (lipoamide) beta
  • Horse(100050581) pyruvate dehydrogenase (lipoamide) beta
  • domestic cat(101100374) pyruvate dehydrogenase (lipoamide) beta
  • dog(476574) pyruvate dehydrogenase (lipoamide) beta
  • chicken(416066) pyruvate dehydrogenase (lipoamide) beta

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PDHB antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Monoclonal Anti-PDHB antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-PDHB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot

Kits

Référence du produit
Description
Espèce(s)
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Espèce(s)
rat, mouse, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PDHB,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Pdhb,
Espèce(s)
mouse