OTX2
orthodenticle homeobox 2
Synonymes:
CPHD6, MCOPS5
Espèce(s):
Human OTX2 (5015), Mouse Otx2 (18424), Rat Otx2 (305858), Zebrafish otx2 (30501), cow OTX2 (538953), domestic cat OTX2 (101094107), chicken OTX2 (395191), dog OTX2 (490708), sheep OTX2 (101114527), domestic guinea pig Otx2 (100729098) ...Plus
ID UniProtKB:
ID du gène:
- Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
- Mouse(18424) orthodenticle homolog 2 (Drosophila)
- Rat(305858) orthodenticle homeobox 2
- Zebrafish(30501) orthodenticle homolog 2
- cow(538953) orthodenticle homeobox 2
- domestic cat(101094107) orthodenticle homeobox 2
- chicken(395191) orthodenticle homeobox 2
- dog(490708) orthodenticle homeobox 2
- sheep(101114527) orthodenticle homeobox 2
- domestic guinea pig(100729098) orthodenticle homeobox 2
- naked mole-rat(101696878) orthodenticle homeobox 2
- Domestic Rabbit(100009374) orthodenticle homeobox 2
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-OTX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anticorps anti-OTX2, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, human, rat, rhesus macaque
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-OTX2 antibody produced in mouse, clone 1H12C4B5, ascites fluid,
Espèces réactives
human
Application
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Anti-OTX2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
western blot
Anti-OTX2 Antibody, clone 1O4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
xenopus, bovine, horse, human, monkey, porcine, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot