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Merck

OAS1

2'-5'-oligoadenylate synthetase 1, 40/46kDa

Synonymes:
IFI-4, OIAS, OIASI
Espèce(s):
Human OAS1 (4938), domestic guinea pig Oas1 (100721851), naked mole-rat Oas1 (101699903), sheep OAS1 (101110181), sheep OAS1 (100294650), dog OAS1 (608778), Horse OAS1 (100034147), domestic cat OAS1 (101087875)
ID UniProtKB:
P00973, A8K4N8, P04820, P29080, P29081, P78485, P78486, Q16700
ID du gène:
  • Human(4938) Summary: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • domestic guinea pig(100721851) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • naked mole-rat(101699903) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • sheep(101110181) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • sheep(100294650) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • dog(608778) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • Horse(100034147) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • domestic cat(101087875) 2'-5'-oligoadenylate synthetase 1, 40/46kDa

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Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA003657
Anti-OAS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
MABC943
Anti-OAS1 Antibody, clone 1D11.1, clone 1D11.1, from mouse,
Espèces réactives
human
Application
western blot
ZRB2141
Anti-OAS1 Antibody, clone 1N2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
ELISA
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
SAB2101669
Anti-OAS1 (ab3) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
western blot
SAB2108190
Anti-OAS1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU158581
MISSION® esiRNA, targeting human OAS1,
Espèce(s)
human
EMU157301
MISSION® esiRNA, targeting mouse Oas1e,
Espèce(s)
mouse