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Merck

MMP7

matrix metallopeptidase 7 (matrilysin, uterine)

Synonymes:
MMP-7, MPSL1, PUMP-1
Espèce(s):
Human MMP7 (4316), Mouse Mmp7 (17393), Rat Mmp7 (25335), chicken MMP7 (418983), dog MMP7 (489432), cow MMP7 (286794), naked mole-rat Mmp7 (101718114), domestic guinea pig Mmp7 (100727130), sheep MMP7 (100192317)
ID UniProtKB:
P09237, Q9BTK9
ID du gène:
  • Human(4316) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17393) matrix metallopeptidase 7
  • Rat(25335) matrix metallopeptidase 7
  • chicken(418983) matrix metallopeptidase 7 (matrilysin, uterine)
  • dog(489432) matrix metallopeptidase 7 (matrilysin, uterine)
  • cow(286794) matrix metallopeptidase 7 (matrilysin, uterine)
  • naked mole-rat(101718114) matrix metallopeptidase 7 (matrilysin, uterine)
  • domestic guinea pig(100727130) matrix metallopeptidase 7 (matrilysin, uterine)
  • sheep(100192317) matrix metallopeptidase 7 (matrilysin, uterine)

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ELISA

Product Number
Description
Espèce(s)
RAB0369
Human MMP-7 ELISA Kit, on for cell culture supernatant,
Espèce(s)
human

Antibodies

Product Number
Description
Espèces réactives
Application
HPA051358
Anti-MMP7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
ZRB2059
Anti-MMP-7 Antibody, clone 2B3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
ELISA
immunocytochemistry
western blot
SAB4501894
Anti-MMP-7 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
IM40
Anti-MMP-7 (Ab-1) Mouse mAb (141-7B2), liquid, clone 141-7B2, Calbiochem®,
Espèces réactives
human
Application
SAB1410789
Anti-MMP7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
proximity ligation assay
western blot

Small Molecule - Inhibitor

Product Number
Description
Espèce(s)
D1822
Doxycycline monohydrate, ,
Espèce(s)
human
1225984
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
M2699
Marimastat, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
P0047
PD166793 hydrate, ≥98% (HPLC),
Espèce(s)
human, rat, mouse

Proteins

Product Number
Description
Espèce(s)
M4565
Matrix Metalloproteinase-7 human, ~0.1 mg/mL, recombinant, expressed in E. coli, buffered aqueous solution,
Espèce(s)
human

esiRNA

Product Number
Description
Espèce(s)
EHU028021
MISSION® esiRNA, targeting human MMP7,
Espèce(s)
human