FZD6
frizzled family receptor 6
- Human(8323) Summary: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]
- Mouse(14368) frizzled homolog 6 (Drosophila)
- Rat(282581) frizzled family receptor 6
- Zebrafish(393533) frizzled homolog 6 (Drosophila)
- cow(445418) frizzled family receptor 6
- dog(403610) frizzled family receptor 6
- domestic cat(101101443) frizzled family receptor 6
- chicken(378788) frizzled family receptor 6
- naked mole-rat(101722552) frizzled family receptor 6
- domestic guinea pig(100719748) frizzled family receptor 6
- sheep(101122197) frizzled family receptor 6
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
immunohistochemistry
immunofluorescence
immunohistochemistry
immunofluorescence