CPN1
carboxypeptidase N, polypeptide 1
- Human(1369) Summary: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
- Mouse(93721) carboxypeptidase N, polypeptide 1
- Rat(365466) carboxypeptidase N, polypeptide 1
- Zebrafish(337172) carboxypeptidase N, polypeptide 1
- dog(477795) carboxypeptidase N, polypeptide 1
- domestic cat(101090390) carboxypeptidase N, polypeptide 1
- cow(536753) carboxypeptidase N, polypeptide 1
- Horse(100070412) carboxypeptidase N, polypeptide 1
- chicken(769143) carboxypeptidase N, polypeptide 1
- naked mole-rat(101718051) carboxypeptidase N, polypeptide 1
- domestic guinea pig(100725809) carboxypeptidase N, polypeptide 1
- sheep(101120287) carboxypeptidase N, polypeptide 1
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