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Merck

ANK2

ankyrin 2, neuronal

Synonymes:
ANK-2, LQT4, brank-2
Espèce(s):
Human ANK2 (287), Mouse Ank2 (109676), Rat Ank2 (362036), fruit fly Ank2 (38863), Horse ANK2 (100064198), domestic cat ANK2 (101100129), chicken ANK2 (422689), dog ANK2 (487908), sheep ANK2 (101115623), domestic guinea pig Ank2 (100717265)
ID UniProtKB:
Q01484, Q01485, Q08AC7, Q08AC8, Q7Z3L5
ID du gène:
  • Human(287) Summary: This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]
  • Mouse(109676) ankyrin 2, brain
  • Rat(362036) ankyrin 2, neuronal
  • fruit fly(38863) Ankyrin 2
  • Horse(100064198) ankyrin 2, neuronal
  • domestic cat(101100129) ankyrin 2, neuronal
  • chicken(422689) ankyrin 2, neuronal
  • dog(487908) ankyrin 2, neuronal
  • sheep(101115623) ankyrin 2, neuronal
  • domestic guinea pig(100717265) ankyrin 2, neuronal
  • naked mole-rat(101697466) ankyrin 2, neuronal

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Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA035970
Anti-ANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
HPA008007
Anti-ANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB5200378
Monoclonal Anti-Ankyrin B - Fitc antibody produced in mouse, clone S105-13, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
SAB5200366
Monoclonal Anti-Ankyrin B antibody produced in mouse, clone S105-13, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
SAB5200367
Monoclonal Anti-Ankyrin B - Atto 390 antibody produced in mouse, clone S105-13, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU079751
MISSION® esiRNA, targeting human ANK2,
Espèce(s)
human
EMU090001
MISSION® esiRNA, targeting mouse Ank2,
Espèce(s)
mouse