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  • Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Chemical communications (Cambridge, England) (2013-02-26)
Lorraine Blackmore, Roisin Moriarty, Ciaran Dolan, Kellie Adamson, Robert J Forster, Marc Devocelle, Tia E Keyes
ABSTRACT

The targeted delivery of luminescent Ru(II) polypyridyl complexes to the nucleus of live mammalian cells by a Nuclear Localisation Signal (NLS) peptide; NF-κB is demonstrated.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ruthenium black
Sigma-Aldrich
Ruthenium, powder
Sigma-Aldrich
Ruthenium, powder, −200 mesh, 99.9% trace metals basis