- Inhibitors of the bacterial cell wall biosynthesis enzyme MurD.
Inhibitors of the bacterial cell wall biosynthesis enzyme MurD.
Bioorganic & medicinal chemistry letters (1999-01-05)
L D Gegnas, S T Waddell, R M Chabin, S Reddy, K K Wong
PMID9873406
ABSTRACT
A series of transition-state analog inhibitors of the D-glutamic acid-adding enzyme (MurD) of bacterial peptidoglycan biosynthesis has been synthesized and evaluated for inhibition of the E. coli enzyme.