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SML1773

Sigma-Aldrich

TYFAVLM trifluoroacetate salt

≥98% (HPLC)

Synonym(s):

P7, Thr-Tyr-Phe-Ala-Val-Leu-Met trifluoroacetate salt, synthetic P7 peptide agonist trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C41H61N7O10S · xC2HF3O2
Molecular Weight:
844.03 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77

Pricing and availability is not currently available.

Quality Level

Assay

≥98% (HPLC)

form

lyophilized powder

storage condition

protect from light

color

white

shipped in

wet ice

storage temp.

−20°C

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form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

Biochem/physiol Actions

Potent and selective agonist of GPR56
TYFAVLM/P7, a synthetic peptides comprising adhesion GPR56 β-strand-13 stalk, is a potent and selective agonist of GPR56. TYFAVLM activates GPR56 in cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Oladapo E Olaniru et al.
Molecular metabolism, 53, 101285-101285 (2021-07-06)
Members of the adhesion G protein-coupled receptor (aGPCR) subfamily are important actors in metabolic processes, with GPR56 (ADGRG1) emerging as a possible target for type 2 diabetes therapy. GPR56 can be activated by collagen III, its endogenous ligand, and by

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