SAB5702100
Anti-Insulin Receptor Antibody, clone 1F1B6, Rabbit Monoclonal
Synonym(s):
CD220,HHF5,INSR
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
Recommended Products
biological source
rabbit
Quality Level
material
colorless
clone
1F1B6, monoclonal
form
liquid
mol wt
100 kDa
species reactivity
human, rat, rat
concentration
1.45 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
General description
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human Insulin Receptor (P06213).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
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