810106C

NBD AA

Avanti Research^™ - A Croda Brand 810106C

• Synonym(s): 20-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino] arachidonic acid
• Empirical Formula (Hill Notation): C₂₆H₃₄ N₄O₅
• CAS Number: 2254005-15-5
• Molecular Weight: 482.57
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (810106C-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 810106C
• concentration: 1 mg/mL (810106C-1mg)
• lipid type: fluorescent lipids; bioactive lipids
• shipped in: dry ice
• storage temp.: −70°C

Description

General description

The endocannabinoid pathway influences behavior, lipogenesis, embryologic development, and pathophysiological effects including pain, inflammation, stress, obesity, and non-alcoholic fatty liver disease. Endogenous endocannabinoids including arachidonoylethanolamide (anandamide, AEA) and 2-arachidonoylglycerol (2-AG) are derived from arachidonic acid (AA). Fluorescent NBD-AA and NBD-AEA analogues are direct probes that can be used for visualizing the uptake, intracellular trafficking, and targeting of these molecules by living cells, as well as measuring the binding of endocannabinoids to cytosolic binding proteins. Importantly, direct binding studies show the affinities of the fluorescent analogues are in the same range as the respective unlabeled ligands. Fluorescent endocannabinoid probes are useful for mapping the impact of various treatments, inhibitors, etc on endocannabinoid uptake and distribution in living cells.

Packaging

5 mL Amber Glass Screw Cap Vial/Argon/Foil Bag 810106C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372
• Precautionary Statements: P260 - P280 - P301 + P312 + P330 - P304 + P340 + P311 - P305 + P351 + P338 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system
• WGK: WGK 3