SLC22A12
solute carrier family 22 (organic anion/urate transporter), member 12
OAT4L, RST, URAT1
Human SLC22A12 (116085), Mouse Slc22a12 (20521), Rat Slc22a12 (365398), Horse SLC22A12 (100055832), dog SLC22A12 (483761), domestic cat SLC22A12 (101100592), domestic guinea pig Slc22a12 (100721051), naked mole-rat Slc22a12 (101714998), cow SLC22A12 (526067), sheep SLC22A12 (101117630)
- Human(116085) Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
- Mouse(20521) solute carrier family 22 (organic anion/cation transporter), member 12
- Rat(365398) solute carrier family 22 (organic anion/urate transporter), member 12
- Horse(100055832) solute carrier family 22 (organic anion/urate transporter), member 12
- dog(483761) solute carrier family 22 (organic anion/urate transporter), member 12
- domestic cat(101100592) solute carrier family 22 (organic anion/urate transporter), member 12
- domestic guinea pig(100721051) solute carrier family 22 (organic anion/urate transporter), member 12
- naked mole-rat(101714998) solute carrier family 22 (organic anion/urate transporter), member 12
- cow(526067) solute carrier family 22 (organic anion/urate transporter), member 12
- sheep(101117630) solute carrier family 22 (organic anion/urate transporter), member 12
Custom & Knockdown Gene Products
siRNA
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Custom Gene Products
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Antibodies
Anti-SLC22A12 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
human
western blot
Anti-SLC22A12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
Monoclonal Anti-SLC22A12 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
human
ELISA
western blot
western blot
Small Molecule - Inhibitor
Sulfinpyrazone for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Benzbromarone, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
human