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Merck

MKNK1

MAP kinase interacting serine/threonine kinase 1

Synonyms:
MNK1
Species:
UniProtKB ID:
Gene ID:
  • Human(8569) Summary: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(17346) MAP kinase-interacting serine/threonine kinase 1
  • Rat(500526) MAP kinase-interacting serine/threonine kinase 1
  • sheep(101104102) MAP kinase interacting serine/threonine kinase 1
  • domestic guinea pig(100720835) MAP kinase interacting serine/threonine kinase 1
  • naked mole-rat(101723982) MAP kinase interacting serine/threonine kinase 1
  • Zebrafish(555974) MAP kinase interacting serine/threonine kinase 1
  • dog(482509) MAP kinase interacting serine/threonine kinase 1
  • cow(525647) MAP kinase interacting serine/threonine kinase 1
  • domestic cat(101082505) MAP kinase interacting serine/threonine kinase 1
  • chicken(771961) MAP kinase interacting serine/threonine kinase 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MKNK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-MKNK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-MNK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
Anti-MNK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-MNK1 antibody produced in rabbit, ~1.4 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
MNK1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mknk1,
Species
mouse
MISSION® esiRNA, targeting human MKNK1,
Species
human