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Merck

MKL1

megakaryoblastic leukemia (translocation) 1

Synonyms:
BSAC, MAL, MRTF-A
Species:
UniProtKB ID:
Gene ID:
  • Human(57591) Summary: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq, Jul 2008]
  • Mouse(223701) MKL (megakaryoblastic leukemia)/myocardin-like 1
  • Rat(315151) megakaryoblastic leukemia (translocation) 1
  • sheep(101102638) megakaryoblastic leukemia (translocation) 1
  • naked mole-rat(101718427) megakaryoblastic leukemia (translocation) 1
  • chicken(418005) megakaryoblastic leukemia (translocation) 1
  • dog(481238) megakaryoblastic leukemia (translocation) 1
  • domestic cat(101086071) megakaryoblastic leukemia (translocation) 1
  • cow(509011) megakaryoblastic leukemia (translocation) 1

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MKL1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-MKL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-MKL1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4281, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mkl1,
Species
mouse
MISSION® esiRNA, targeting human MKL1,
Species
human