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Merck

KMT2D

lysine (K)-specific methyltransferase 2D

Synonyms:
AAD10, ALR, CAGL114, KABUK1, KMS, MLL2, MLL4, TNRC21
Species:
Human KMT2D (8085), Mouse Kmt2d (381022), Rat Kmt2d (100362634), Zebrafish kmt2d (100158249), cow KMT2D (506805), domestic guinea pig Kmt2d (100728357), naked mole-rat Kmt2d (101718411)
UniProtKB ID:
O14686, O14687
Gene ID:
  • Human(8085) Summary: The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]
  • Mouse(381022) lysine (K)-specific methyltransferase 2D
  • Rat(100362634) lysine (K)-specific methyltransferase 2D
  • Zebrafish(100158249) lysine (K)-specific methyltransferase 2D
  • cow(506805) lysine (K)-specific methyltransferase 2D
  • domestic guinea pig(100728357) lysine (K)-specific methyltransferase 2D
  • naked mole-rat(101718411) lysine (K)-specific methyltransferase 2D

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
AMAB91368
Monoclonal Anti-KMT2D antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5346, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
ABE206
Anti-MLL2 (C-Term) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot
ZRB1538
Anti-MLL2 Antibody, clone 3L17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, horse, human, monkey, mouse, zebrafish
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU076961
MISSION® esiRNA, targeting human KMT2D,
Species
human