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Merck

IRAK3

interleukin-1 receptor-associated kinase 3

Synonyms:
ASRT5, IRAKM
Species:
UniProtKB ID:
Gene ID:
  • Human(11213) Summary: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
  • Mouse(73914) interleukin-1 receptor-associated kinase 3
  • Rat(314870) interleukin-1 receptor-associated kinase 3
  • domestic guinea pig(100729478) interleukin-1 receptor-associated kinase 3
  • naked mole-rat(101704873) interleukin-1 receptor-associated kinase 3
  • sheep(101115273) interleukin-1 receptor-associated kinase 3
  • Zebrafish(567444) interleukin-1 receptor-associated kinase 3
  • cow(510342) interleukin-1 receptor-associated kinase 3
  • domestic cat(101093197) interleukin-1 receptor-associated kinase 3
  • dog(481150) interleukin-1 receptor-associated kinase 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IRAK3, (C-terminal) antibody produced in mouse, clone 1F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-IRAK3 antibody produced in mouse, clone 1F1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
ANTI-IRAK3 antibody produced in mouse, clone 1C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
ANTI-IRAK3 antibody produced in mouse, clone 1G11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-IRAK3 antibody produced in mouse, clone 1A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Irak3,
Species
mouse
MISSION® esiRNA, targeting human IRAK3,
Species
human