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Merck

HTRA2

HtrA serine peptidase 2

Synonyms:
OMI, PARK13, PRSS25
Species:
UniProtKB ID:
Gene ID:
  • Human(27429) Summary: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(64704) HtrA serine peptidase 2
  • Rat(297376) HtrA serine peptidase 2
  • fruit fly(41756) CG8464 gene product from transcript CG8464-RB
  • chicken(395990) HtrA serine peptidase 2
  • dog(475782) HtrA serine peptidase 2
  • domestic cat(768259) HtrA serine peptidase 2
  • cow(523039) HtrA serine peptidase 2
  • domestic guinea pig(100734064) HtrA serine peptidase 2
  • naked mole-rat(101725239) HtrA serine peptidase 2
  • sheep(101120228) HtrA serine peptidase 2
  • Domestic Rabbit(100338967) HtrA serine peptidase 2

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ELISA

Product Number
Description
Species
Human HTRA2 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HTRA2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
Anti-HTRA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-HtrA2 (OMI) (N-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-OMI (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-HTRA2, (C-terminal) antibody produced in mouse, clone 3G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HTRA2,
Species
human