Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

SML0154

Sigma-Aldrich

SPV-106

≥98% (HPLC)

Synonym(s):

2-Pentadecylidene-Propanedioic acid 1,3-diethyl ester, Pentadecylidenemalonate 1b

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H40O4
CAS Number:
1036939-38-4
Molecular Weight:
368.55
MDL number:
MFCD20527327
UNSPSC Code:
12352200
PubChem Substance ID:
329825202
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

oil

color

colorless

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCC\C=C(\C(=O)OCC)C(=O)OCC

InChI

1S/C22H40O4/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21(23)25-5-2)22(24)26-6-3/h19H,4-18H2,1-3H3

InChI key

APIJHPAXMCKJBY-UHFFFAOYSA-N

Biochem/physiol Actions

SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. The compound inhibits the activity of p300/CBP, but potentiates p300/CBP-associated factor (PCAF) activity. SPV106 also induces S-phase cell cycle arrest and apoptosis in U937 cells.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Histone Modification and Chromatin Remodeling | Epigenetics

Epigenetic modifications are thought to occur through two key interconnected processes—DNA methylation and the covalent modification of histones.

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service