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SCT211

Sigma-Aldrich

BioTracker Green Sulfane Sulfur live cell dye

Live Cell imaging probe for sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-S<sub>n</sub>-S-R) and ploysulfide (H<sub>2</sub>S<sub>n</sub>).

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About This Item

UNSPSC Code:
12352207

form

lyophilized

application(s)

cell analysis

detection method

fluorometric

General description

Intracellularly abundant sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-Sn-S-R) and polysulfide (H2Sn) play important roles to maintain intracellular reducing environments. BioTracker Green Sulfane Sulfur Live Cell Dye is a FRET-based fluorescence probe to specifically detect the intracellular sulfane sulfur species. It shows only weak fluorescence without sulfane sulfur, and reversibly fluoresces in response to micromolar concentrations of sulfane sulfur. Its reaction is highly specific and has minimal to no reactivity with H2S, cysteine residues, and sulfur oxides. The dye is a cell permeable diacetylated form which is hydrolyzed by intracellular esterases to generate a metabolite which is retained within the cells. Thus it is suitable to monitor intracellular concentration of sulfane sulfur via live-cell imaging.Spectral Properties:Absorbance (max): 495nmEmission (max): 525nmResearch Category:Live Cell Dye

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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