PTPRS
protein tyrosine phosphatase, receptor type, S
Synonyms:
PTPSIGMA
Species:
Human PTPRS (5802), Mouse Ptprs (19280), Rat Ptprs (25529), naked mole-rat Ptprs (101715786), cow PTPRS (537480), sheep PTPRS (101112817), chicken PTPRS (396375), dog PTPRS (485030), Horse PTPRS (100069183), domestic cat PTPRS (101083913)
UniProtKB ID:
Gene ID:
- Human(5802) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
- Mouse(19280) protein tyrosine phosphatase, receptor type, S
- Rat(25529) protein tyrosine phosphatase, receptor type, S
- naked mole-rat(101715786) protein tyrosine phosphatase, receptor type, S
- cow(537480) protein tyrosine phosphatase, receptor type, S
- sheep(101112817) protein tyrosine phosphatase, receptor type, S
- chicken(396375) protein tyrosine phosphatase, receptor type, S
- dog(485030) protein tyrosine phosphatase, receptor type, S
- Horse(100069183) protein tyrosine phosphatase, receptor type, S
- domestic cat(101083913) protein tyrosine phosphatase, receptor type, S
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPRS Antibody, Clone 9H3.1, clone 9H3.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species
PTPsigma/PTPRS Active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species