Skip to Content
Merck

KLC1

kinesin light chain 1

Synonyms:
KLC, KNS2, KNS2A
Species:
UniProtKB ID:
Gene ID:
  • Human(3831) Summary: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(16593) kinesin light chain 1
  • Rat(171041) kinesin light chain 1
  • chicken(423484) kinesin light chain 1
  • cow(508999) kinesin light chain 1
  • Horse(100055290) kinesin light chain 1
  • domestic cat(101099130) kinesin light chain 1
  • dog(480446) kinesin light chain 1
  • sheep(101102677) kinesin light chain 1
  • domestic guinea pig(100736081) kinesin light chain 1
  • naked mole-rat(101710626) kinesin light chain 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-KLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
ANTI-KLC1 (CENTER) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

western blot
Anti-Kinesin Light Chain Antibody, clone 63-90, clone 63-90, from mouse,
Species Reactivity
mouse, rat, squid
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Kinesin light chain 1 (KLC1) Antibody, clone 5C3P5, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Klc1,
Species
mouse
MISSION® esiRNA, targeting human KLC1, RP11-73M18.2,
Species
human