Skip to Content
Merck
  • Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical

Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical

Clinica chimica acta; international journal of clinical chemistry (2017-01-17)
M Mirzaian, P Wisse, M J Ferraz, A R A Marques, P Gaspar, S V Oussoren, K Kytidou, J D C Codée, G van der Marel, H S Overkleeft, J M Aerts
PMID28089753
ABSTRACT

Free sphingoid bases (lysosphingolipids) of primary storage sphingolipids are increased in tissues and plasma of several sphingolipidoses. As shown earlier by us, sphingoid bases can be accurately quantified using UPLC-ESI-MS/MS, particularly in combination with identical