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  • Bacteremia due to imipenem-resistant Roseomonas mucosa in a child with acute lymphoblastic leukemia.

Bacteremia due to imipenem-resistant Roseomonas mucosa in a child with acute lymphoblastic leukemia.

Journal of pediatric hematology/oncology (2013-05-15)
Anne-Laure Michon, Laure Saumet, Alice Bourdier, Stéphanie Haouy, Nicolas Sirvent, Hélène Marchandin
ABSTRACT

Roseomonas are described as opportunistic pathogens rarely involved in human infections. Their identification requires molecular methods and their antimicrobial susceptibility pattern varies according to the species. We report the first case of bacteremia due to Roseomonas mucosa in a child with leukemia and reviewed pediatric cases of Roseomonas infection, for which undoubted strain identification was available. Favorable outcome was observed despite resistance to numerous β-lactams that may account for delayed effective treatment, suggesting the low virulence of Roseomonas in children. Here, the strain also displayed unusual resistance to imipenem, highlighting the possible acquisition of additional resistance by this pathogen.

MATERIALS
Product Number
Brand
Product Description

USP
Imipenem monohydrate, United States Pharmacopeia (USP) Reference Standard
Sigma-Aldrich
Imipenem monohydrate, ≥98% (HPLC)